What is THC-H?

The world of cannabis is dynamic, with continual discoveries and advancements. One of the latest entrants that has sparked interest among researchers and cannabis enthusiasts is Tetrahydrocannabihexol, more commonly referred to as THC-H.

what is THC-H

The genesis and structure of THC-H

THC-H, a variant of the well-known Delta 9 THC, was brought to light in 2020 by a team of dedicated Italian researchers. These scientists had previously successfully isolated other cannabinoids, namely THCP and CBDP.

Interested about what is Delta-8, and the difference between delta-9?

THC-H shares a similar structure and function to Delta 9 THC, but it is unique in possessing an n-hexyl side chain. This distinctive feature marks THC-H as the first-ever discovered hexyl derivative of cannabinoids.

A new player in the cannabis industry

THC-H discovery has significantly contributed to the ever-growing list of cannabinoids, which now totals over 150. This constant expansion of knowledge about the cannabis plant’s compounds is driven by the relentless quest to find potent, safe, and legal alternatives to Delta 9 THC, which is currently federally prohibited.

The production process

THC-H can be derived in two ways—naturally or synthetically. However, synthetic production takes precedence in consumer products due to the compound’s low concentration in plant matter, making natural extraction challenging. It’s widely believed that hemp-based CBD is converted into THC, which is further transformed into THC-H.

Potential effects and benefits of THC-H

While the exact effects and benefits of THC-H are still under extensive research, initial reports suggest that it may be effective in elevating mood and relieving pain. Preliminary studies on mice have shown that THC-H can block neural pathways responsible for pain detection, preventing our brains from recognizing pain.

However, more comprehensive research is needed to confirm these findings and explore their potential for providing mental health relief.

Unveil how much THC is in a hit of weed.

The unexpected discovery of CBD-H

Interestingly, researchers also stumbled upon CBD-H during the same experiment that led to the THC-H discovery. Unlike other compounds in the same family, such as CBD and CBDP, CBD-H binds directly to CB receptors. This unique property could potentially make its pharmacological benefits greater than CBD.

Assessing the potency

In terms of potency, THC-H is believed to be more potent than Delta 9 THC but slightly less potent than THCP. However, these are early days, and more research is needed to fully understand the effects and potential benefits of this new cannabinoid.
THC-H definition

The current state of THC-H products

By federal legislation, tetrahydrocannabihexol (THC-H) is considered a legal cannabinoid as long as it originates from the hemp plant, which is the case for all commercially available THC-H products. This legality was established by the 2018 Farm Bill, which is the same law that legalized cannabinoids such as CBD and Delta 8.

The Farm Bill stipulates that all hemp derivatives are permissible if they contain no more than 0.3% Delta 9 THC by dry weight. Since THC-H is a distinct cannabinoid from Delta 9, there are no legal complications.

However, it is important to note that several states have implemented comprehensive bans on psychoactive cannabinoids. Consequently, if you reside in any of the following states, the sale of THC-H to you would not be legally permitted:

  • Alaska
  • Arizona
  • Arkansas
  • Colorado
  • Delaware
  • Idaho
  • Iowa
  • Mississippi
  • Montana
  • Nevada
  • New York
  • North Dakota
  • Oregon
  • Rhode Island
  • Utah
  • Vermont
  • Washington

The future of THC-H

In conclusion, THC-H is a promising new addition to the cannabinoid family. Its potential for pain relief, mood elevation, and its unique chemical structure make it an exciting study area for researchers. As we delve deeper into the vast and complex world of cannabis, compounds like THC-H bring us one step closer to fully unlocking the plant’s potential.


What is THC-H?

THC-H, or Tetrahydrocannabihexol, is a newly discovered cannabinoid with a similar structure and function to Delta 9 THC but a unique n-hexyl side chain.

Who discovered THC-H?

THC-H was discovered in 2020 by a team of Italian researchers who had previously isolated other cannabinoids, such as THCP and CBDP.

How is THC-H produced?

THC-H can be produced both naturally and synthetically. However, due to its low concentration in plant matter, synthetic production is more common in consumer products.

What are the potential benefits of THC-H?

While research is ongoing, initial reports suggest that THC-H may effectively elevate mood and relieve pain. It’s believed to block neural pathways that are responsible for pain detection.

How does THC-H compare to other cannabinoids in terms of potency?

THC-H is believed to be more potent than Delta 9 THC but slightly less potent than THCP. However, more research is needed to fully understand the effects and potential benefits of this new cannabinoid.

Alex Ramsey

Alex Ramsey

Cannabis Industry Copywriting Specialist

He combines a deep understanding of cannabis with a passion for crafting engaging content. With a focus on demystifying cannabis through education, Alex contributes to the industry’s growth with content that sells, educates, and engages the community.

Learn more about 420 Ergonomics, our team.

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